Detalhe da pesquisa
1.
Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces.
PLoS Pathog
; 20(4): e1012175, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38640117
2.
Transcription elongation mechanisms of RNA polymerases I, II, and III and their therapeutic implications.
J Biol Chem
; 300(3): 105737, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38336292
3.
Transient-State Kinetic Analysis of the RNA Polymerase II Nucleotide Incorporation Mechanism.
Biochemistry
; 62(1): 95-108, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36525636
4.
The small-molecule BMH-21 directly inhibits transcription elongation and DNA occupancy of RNA polymerase I in vivo and in vitro.
J Biol Chem
; 298(1): 101450, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34838819
5.
Rate of transcription elongation and sequence-specific pausing by RNA polymerase I directly influence rRNA processing.
J Biol Chem
; 298(12): 102730, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36423683
6.
Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress.
J Biol Chem
; 298(12): 102690, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36372232
7.
Biphasic pleural mesothelioma in a goat.
Can Vet J
; 64(9): 828-832, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37663018
8.
Defining the divergent enzymatic properties of RNA polymerases I and II.
J Biol Chem
; 296: 100051, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168625
9.
Coordinated Control of rRNA Processing by RNA Polymerase I.
Trends Genet
; 35(10): 724-733, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31358304
10.
Iron Reduction in Dermacentor andersoni Tick Cells Inhibits Anaplasma marginale Replication.
Int J Mol Sci
; 23(7)2022 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409307
11.
The N-terminal domain of the A12.2 subunit stimulates RNA polymerase I transcription elongation.
Biophys J
; 120(10): 1883-1893, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737158
12.
Transient-state kinetic analysis of multi-nucleotide addition catalyzed by RNA polymerase I.
Biophys J
; 120(20): 4378-4390, 2021 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509510
13.
Caprine PRNP polymorphisms N146S and Q222K are associated with proteolytic cleavage of PrPC.
Genet Sel Evol
; 53(1): 52, 2021 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34147084
14.
NETSeq reveals heterogeneous nucleotide incorporation by RNA polymerase I.
Proc Natl Acad Sci U S A
; 115(50): E11633-E11641, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30482860
15.
Discovery of novel inhibitors of ribosome biogenesis by innovative high throughput screening strategies.
Biochem J
; 476(15): 2209-2219, 2019 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31341008
16.
A Novel Assay for RNA Polymerase I Transcription Elongation Sheds Light on the Evolutionary Divergence of Eukaryotic RNA Polymerases.
Biochemistry
; 58(16): 2116-2124, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30912638
17.
The A12.2 Subunit Is an Intrinsic Destabilizer of the RNA Polymerase I Elongation Complex.
Biophys J
; 114(11): 2507-2515, 2018 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29874602
18.
A Mycobacterium avium subsp. paratuberculosis relA deletion mutant and a 35 kDa major membrane protein elicit development of cytotoxic T lymphocytes with ability to kill intracellular bacteria.
Vet Res
; 49(1): 53, 2018 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941017
19.
Multisubunit RNA Polymerase Cleavage Factors Modulate the Kinetics and Energetics of Nucleotide Incorporation: An RNA Polymerase I Case Study.
Biochemistry
; 56(42): 5654-5662, 2017 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28846843
20.
The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I.
J Biol Chem
; 291(6): 3010-8, 2016 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26663077